Publications
Click here for the full Abounader Lab bibliography
2023
Myron K Gibert Jr, Ying Zhang, Shekhar Saha, Pawel Marcinkiewicz, Collin Dube, Kadie Hudson, Yunan Sun, Sylwia Bednarek, Bilhan Chagari, Aditya Sarkar, Christian Roig-Laboy, Natalie Neace, Karim Saoud, Initha Setiady, Farina Hanif, Pankaj Kumar, Benjamin Kefas, Roger Abounader, A first comprehensive analysis of Transcribed Ultra Conserved Regions uncovers important regulatory functions of novel non-coding transcripts in gliomas. bioRxiv, 2023: p. 2023.09.12.557444.
Hanif F, Zhang Y, Dube C, Gibert MK Jr, Saha S, Hudson K, Marcinkiewicz P, Kefas B, Guessous F, Abounader R. miR-3174 is a new tumor suppressor microRNA that inhibits several
oncogenes in glioblastoma. Int J Mol Sci, 2023. 24(11).
2022
Gibert MK Jr, Sarkar A, Chagari B, Roig-Laboy C, Saha S, Bednarek S, Kefas B, Hanif F, Hudson K, Dube C, Zhang Y, Abounader R. Transcribed Ultraconserved Regions in Cancer. Cells. 2022 May 19;11(10):1684. doi: 10.3390/cells11101684. PMID: 35626721; PMCID: PMC9139194.
Mulcahy EQX, Zhang Y, Colόn RR, Cain SR, Gibert MK Jr, Dube CJ, Hafner M, Abounader R. MicroRNA 3928 Suppresses Glioblastoma through Downregulation of Several Oncogenes and Upregulation of p53. Int J Mol Sci. 2022 Apr 1;23(7):3930. doi: 10.3390/ijms23073930. PMID: 35409289; PMCID: PMC8998958.
2021
Saha S, Zhang Y, Wilson B, Abounader R, Dutta A. The tumor-suppressive long noncoding RNA DRAIC inhibits protein translation and induces autophagy by activating AMPK. J Cell Sci. 2021 Dec 15;134(24):jcs259306. doi: 10.1242/jcs.259306. Epub 2021 Dec 20. PMID: 34746949; PMCID: PMC8729785.
Abounader R, Schiff D. The blood-brain barrier limits the therapeutic efficacy of antibody-drug conjugates in glioblastoma. Neuro Oncol. 2021 Dec 1;23(12):1993-1994. doi: 10.1093/neuonc/noab223. PMID: 34515791; PMCID: PMC8643443.
Abounader R, Schiff D. A new class of radiosensitizers for glioblastoma. Oncotarget. 2021 Jun 22;12(13):1199-1200. doi: 10.18632/oncotarget.27970. PMID: 34194618; PMCID: PMC8238247.
El Founini Y, Chaoui I, Dehbi H, El Mzibri M, Abounader R, Guessous F. MicroRNAs: Key Regulators in Lung Cancer. Microrna. 2021;10(2):109-122. doi: 10.2174/2211536610666210527102522. PMID: 34047262.
2020
Mulcahy EQX, Colόn RR, Abounader R. HGF/MET Signaling in Malignant Brain Tumors. Int J Mol Sci. 2020 Oct 13;21(20). doi: 10.3390/ijms21207546. Review. PubMed PMID: 33066121; PubMed Central PMCID: PMC7590206.
Ngulde SI, Sandabe UK, Abounader R, Zhang Y, Hussaini IM. Activities of Some Medicinal Plants on the Proliferation and Invasion of Brain Tumor Cell Lines. Adv Pharmacol Pharm Sci. 2020;2020:3626879. doi: 10.1155/2020/3626879. eCollection 2020. PubMed PMID: 32908971; PubMed Central PMCID: PMC7474344.
Bannon DI, Bao W, Turner SD, McCain WC, Dennis W, Wolfinger R, Perkins E, Abounader R. Gene expression in mouse muscle over time after nickel pellet implantation. Metallomics. 2020 Apr 1;12(4):528-538. doi: 10.1039/c9mt00289h. Epub 2020 Feb 17. PubMed PMID: 32065191.
2019
Ngulde SI, Sandabe UK, Abounader R, Dawson TK, Zhang Y, Iliya I, Hussaini IM, Ethanol Extract of Securidaca longipedunculata Induces Apoptosis in Brain Tumor (U87) Cells., 2019; BioMed research international. 2019() 9826590. PMID: 30931334 | PMCID: PMC6413385
Yang Y, Dodbele S, Park T, Glass R, Bhat K, Sulman EP, Zhang Y, Abounader R, MicroRNA-29a inhibits glioblastoma stem cells and tumor growth by regulating the PDGF pathway., 2019; Journal of neuro-oncology. 145(1) 23-34. PMID: 31482267
Jung J, Zhang Y, Celiku O, Zhang W, Song H, Williams BJ, Giles AJ, Rich JN, Abounader R, Gilbert MR, Park DM, Mitochondrial NIX Promotes Tumor Survival in the Hypoxic Niche of Glioblastoma., 2019; Cancer research. 79(20) 5218-5232. PMID: 31488423 | PMCID: PMC6801103
Cruickshanks N, Zhang Y, Hine S, Gibert M, Yuan F, Oxford M, Grello C, Pahuski M, Dube C, Guessous F, Wang B, Deveau C, Saoud K, Gallagher I, Wulfkuhle J, Schiff D, Phan S, Petricoin E, Abounader R, Discovery and Therapeutic Exploitation of Mechanisms of Resistance to MET Inhibitors in Glioblastoma., 2019; Clinical cancer research : an official journal of the American Association for Cancer Research. 25(2) 663-673. PMID: 30201763 | PMCID: PMC6335175
2018
Olmez I, Zhang Y, Manigat L, Benamar M, Brenneman B, Nakano I, Godlewski J, Bronisz A, Lee J, Abbas T, Abounader R, Purow B, Combined c-Met/Trk Inhibition Overcomes Resistance to CDK4/6 Inhibitors in Glioblastoma., 2018; Cancer research. 78(15) 4360-4369. PMID: 29844123 | PMCID: PMC6072607
Zhang Y, Dube C, Gibert M, Cruickshanks N, Wang B, Coughlan M, Yang Y, Setiady I, Deveau C, Saoud K, Grello C, Oxford M, Yuan F, Abounader R, The p53 Pathway in Glioblastoma., 2018; Cancers. 10(9) . PMID: 30200436 | PMCID: PMC6162501
Zhang Y, Kim J, Mueller AC, Dey B, Yang Y, Lee DH, Hachmann J, Finderle S, Park DM, Christensen J, Schiff D, Purow B, Dutta A, Abounader R, Correction to: Multiple receptor tyrosine kinases converge on microRNA-134 to control KRAS, STAT5B, and glioblastoma., 2018; Cell death and differentiation. 26(1) 197. PMID: 29899381 | PMCID: PMC6294759
Abounader R, A new practical and versatile mouse model of proneural glioblastoma., 2018; Neuro-oncology. 20(3) 299-301. PMID: 29432618 | PMCID: PMC5817963
Melhuish TA, Kowalczyk I, Manukyan A, Zhang Y, Shah A, Abounader R, Wotton D, Myt1 and Myt1l transcription factors limit proliferation in GBM cells by repressing YAP1 expression., 2018; Biochimica et biophysica acta. Gene regulatory mechanisms. 1861(11) 983-995. PMID: 30312684 | PMCID: PMC6203443
Gonzalez PP, Kim J, Galvao RP, Cruickshanks N, Abounader R, Zong H, p53 and NF 1 loss plays distinct but complementary roles in glioma initiation and progression., 2018; Glia. 66(5) 999-1015. PMID: 29392777
2017
Zhang Y, Cruickshanks N, Yuan F, Wang B, Pahuski M, Wulfkuhle J, Gallagher I, Koeppel AF, Hatef S, Papanicolas C, Lee J, Bar EE, Schiff D, Turner SD, Petricoin EF, Gray LS, Abounader R, Targetable T-type Calcium Channels Drive Glioblastoma., 2017; Cancer research. 77(13) 3479-3490. PMID: 28512247 | PMCID: PMC5505315
Cruickshanks N, Zhang Y, Yuan F, Pahuski M, Gibert M, Abounader R, Role and Therapeutic Targeting of the HGF/MET Pathway in Glioblastoma., 2017; Cancers. 9(7) . PMID: 28696366 | PMCID: PMC5532623
Olmez I, Brenneman B, Xiao A, Serbulea V, Benamar M, Zhang Y, Manigat L, Abbas T, Lee J, Nakano I, Godlewski J, Bronisz A, Abounader R, Leitinger N, Purow B, Combined CDK4/6 and mTOR Inhibition Is Synergistic against Glioblastoma via Multiple Mechanisms., 2017; Clinical cancer research : an official journal of the American Association for Cancer Research. 23(22) 6958-6968. PMID: 28814434 | PMCID: PMC5690820
Olmez I, Love S, Xiao A, Manigat L, Randolph P, McKenna BD, Neal BP, Boroda S, Li M, Brenneman B, Abounader R, Floyd D, Lee J, Nakano I, Godlewski J, Bronisz A, Sulman EP, Mayo M, Gioeli D, Weber M, Harris TE, Purow B, Targeting the mesenchymal subtype in glioblastoma and other cancers via inhibition of diacylglycerol kinase alpha., 2017; Neuro-oncology. () . PMID: 29048560 | PMCID: PMC5777487
2016
Vega RA, Zhang Y, Curley C, Price RL, Abounader R, 370 Magnetic Resonance-Guided Focused Ultrasound Delivery of Polymeric Brain-Penetrating Nanoparticle MicroRNA Conjugates in Glioblastoma., 2016; Neurosurgery. 63() 210. PMID: 27399567
Reon BJ, Anaya J, Zhang Y, Mandell J, Purow B, Abounader R, Dutta A, Expression of lncRNAs in Low-Grade Gliomas and Glioblastoma Multiforme: An In Silico Analysis., 2016; PLoS medicine. 13(12) e1002192. PMID: 27923049 | PMCID: PMC5140055
2015
Lee DH, Zhang Y, Kassam AB, Park MJ, Gardner P, Prevedello D, Henry S, Horbinski C, Beumer JH, Tawbi H, Williams BJ, Shaffrey ME, Egorin MJ, Abounader R, Park DM, Combined PDGFR and HDAC Inhibition Overcomes PTEN Disruption in Chordoma., 2015; PloS one. 10(8) e0134426. PMID: 26247786 | PMCID: PMC4527706
2014
Floyd DH, Zhang Y, Dey BK, Kefas B, Breit H, Marks K, Dutta A, Herold-Mende C, Synowitz M, Glass R, Abounader R, Purow BW, Novel anti-apoptotic microRNAs 582-5p and 363 promote human glioblastoma stem cell survival via direct inhibition of caspase 3, caspase 9, and Bim., 2014; PloS one. 9(5) e96239. PMID: 24805821 | PMCID: PMC4013090
Kim J, Zhang Y, Skalski M, Hayes J, Kefas B, Schiff D, Purow B, Parsons S, Lawler SE, Abounader R, microRNA-148a is a prognostic oncomiR that targets MIG6 and BIM to regulate EGFR and apoptosis in glioblastoma., 2014; Cancer research. () . PMID: 24425048 | PMCID: PMC3947487
Zhang Y, Kim J, Mueller AC, Dey B, Yang Y, Lee DH, Hachmann J, Finderle S, Park DM, Christensen J, Schiff D, Purow B, Dutta A, Abounader R, Multiple receptor tyrosine kinases converge on microRNA-134 to control KRAS, STAT5B, and glioblastoma., 2014; Cell death and differentiation. 21(5) 720-34. PMID: 24440911 | PMCID: PMC3978301
Feng C, Zhang Y, Yin J, Li J, Abounader R, Zuo Z, Regulatory factor X1 is a new tumor suppressive transcription factor that acts via direct downregulation of CD44 in glioblastoma., 2014; Neuro-oncology. 16(8) 1078-85. PMID: 24526308 | PMCID: PMC4096175
Zhang Y, Schiff D, Park D, Abounader R, MicroRNA-608 and microRNA-34a regulate chordoma malignancy by targeting EGFR, Bcl-xL and MET., 2014; PloS one. 9(3) e91546. PMID: 24621885 | PMCID: PMC3951453
Negishi M, Wongpalee SP, Sarkar S, Park J, Lee KY, Shibata Y, Reon BJ, Abounader R, Suzuki Y, Sugano S, Dutta A, A New lncRNA, APTR, Associates with and Represses the CDKN1A/p21 Promoter by Recruiting Polycomb Proteins., 2014; PloS one. 9(4) e95216. PMID: 24748121 | PMCID: PMC3991591
Awad AJ, Burns TC, Zhang Y, Abounader R, Targeting MET for glioma therapy., 2014; Neurosurgical focus. 37(6) E10. PMID: 25434379
2013
Guessous F, Alvarado-Velez M, Marcinkiewicz L, Zhang Y, Kim J, Heister S, Kefas B, Godlewski J, Schiff D, Purow B, Abounader R, Oncogenic effects of miR-10b in glioblastoma stem cells., 2013; Journal of neuro-oncology. 112(2) 153-63. PMID: 23307328 | PMCID: PMC3609924
Dominguez CL, Floyd DH, Xiao A, Mullins GR, Kefas BA, Xin W, Yacur MN, Abounader R, Lee JK, Wilson GM, Harris TE, Purow BW, Diacylglycerol kinase α is a critical signaling node and novel therapeutic target in glioblastoma and other cancers., 2013; Cancer discovery. 3(7) 782-97. PMID: 23558954 | PMCID: PMC3710531
Kofman AV, Letson C, Dupart E, Bao Y, Newcomb WW, Schiff D, Brown J, Abounader R, The p53-microRNA-34a axis regulates cellular entry receptors for tumor-associated human herpes viruses., 2013; Medical hypotheses. 81(1) 62-7. PMID: 23643704 | PMCID: PMC3676726
Huang X, Zhang Y, Tang Y, Butler N, Kim J, Guessous F, Schiff D, Mandell J, Abounader R, A novel PTEN/mutant p53/c-Myc/Bcl-XL axis mediates context-dependent oncogenic effects of PTEN with implications for cancer prognosis and therapy., 2013; Neoplasia (New York, N.Y.). 15(8) 952-65. PMID: 23908595 | PMCID: PMC3730046
Kofman AV, Kim J, Park SY, Dupart E, Letson C, Bao Y, Ding K, Chen Q, Schiff D, Larner J, Abounader R, microRNA-34a promotes DNA damage and mitotic catastrophe., 2013; Cell cycle (Georgetown, Tex.). 12(22) 3500-11. PMID: 24091633 | PMCID: PMC3906336
Kefas B, Floyd DH, Comeau L, Frisbee A, Dominguez C, Dipierro CG, Guessous F, Abounader R, Purow B, A miR-297/hypoxia/DGK-α axis regulating glioblastoma survival., 2013; Neuro-oncology. 15(12) 1652-63. PMID: 24158111 | PMCID: PMC3829588
2011
Kofman A, Marcinkiewicz L, Dupart E, Lyshchev A, Martynov B, Ryndin A, Kotelevskaya E, Brown J, Schiff D, Abounader R, The roles of viruses in brain tumor initiation and oncomodulation., 2011; Journal of neuro-oncology. 105(3) 451-66. PMID: 21720806 | PMCID: PMC3278219
Kofman AV, Abounader R, When tumor cells make blood vessels: implications for glioblastoma therapy., 2011; Future oncology (London, England). 7(7) 841-3. PMID: 21732755 | PMCID: PMC3278210
Catania A, Maira F, Skarmoutsou E, D'Amico F, Abounader R, Mazzarino MC, Insight into the role of microRNAs in brain tumors (review)., 2011; International journal of oncology. 40(3) 605-24. PMID: 22179098
Guessous F, Yang Y, Johnson E, Marcinkiewicz L, Smith M, Zhang Y, Kofman A, Schiff D, Christensen J, Abounader R, Cooperation between c-Met and focal adhesion kinase family members in medulloblastoma and implications for therapy., 2011; Molecular cancer therapeutics. 11(2) 288-97. PMID: 22188814 | PMCID: PMC3277676
Zhang Y, Dutta A, Abounader R, The role of microRNAs in glioma initiation and progression., 2011; Frontiers in bioscience : a journal and virtual library. 17() 700-12. PMID: 22201769 | PMCID: PMC3278211
2010
Guessous F, Zhang Y, Kofman A, Catania A, Li Y, Schiff D, Purow B, Abounader R, microRNA-34a is tumor suppressive in brain tumors and glioma stem cells., 2010; Cell cycle (Georgetown, Tex.). 9(6) 1031-6. PMID: 20190569 | PMCID: PMC3278213
Zhang Y, Guessous F, Kofman A, Schiff D, Abounader R, XL-184, a MET, VEGFR-2 and RET kinase inhibitor for the treatment of thyroid cancer, glioblastoma multiforme and NSCLC., 2010; IDrugs : the investigational drugs journal. 13(2) 112-21. PMID: 20127563 | PMCID: PMC3268517
2009
Guessous F, Zhang Y, diPierro C, Marcinkiewicz L, Sarkaria J, Schiff D, Buchanan S, Abounader R, An orally bioavailable c-Met kinase inhibitor potently inhibits brain tumor malignancy and growth., 2009; Anti-cancer agents in medicinal chemistry. 10(1) 28-35. PMID: 20015006 | PMCID: PMC3278215
Li Y, Guessous F, DiPierro C, Zhang Y, Mudrick T, Fuller L, Johnson E, Marcinkiewicz L, Engelhardt M, Kefas B, Schiff D, Kim J, Abounader R, Interactions between PTEN and the c-Met pathway in glioblastoma and implications for therapy., 2009; Molecular cancer therapeutics. 8(2) 376-85. PMID: 19190120
Abounader R, Interactions between PTEN and receptor tyrosine kinase pathways and their implications for glioma therapy., 2009; Expert review of anticancer therapy. 9(2) 235-45. PMID: 19192961 | PMCID: PMC2678856
Li Y, Guessous F, Zhang Y, Dipierro C, Kefas B, Johnson E, Marcinkiewicz L, Jiang J, Yang Y, Schmittgen TD, Lopes B, Schiff D, Purow B, Abounader R, MicroRNA-34a inhibits glioblastoma growth by targeting multiple oncogenes., 2009; Cancer research. 69(19) 7569-76. PMID: 19773441 | PMCID: PMC2756313
Kefas B, Comeau L, Floyd DH, Seleverstov O, Godlewski J, Schmittgen T, Jiang J, diPierro CG, Li Y, Chiocca EA, Lee J, Fine H, Abounader R, Lawler S, Purow B, The neuronal microRNA miR-326 acts in a feedback loop with notch and has therapeutic potential against brain tumors., 2009; The Journal of neuroscience : the official journal of the Society for Neuroscience. 29(48) 15161-8. PMID: 19955368 | PMCID: PMC2823067
Guessous F, Zhang Y, diPierro C, Marcinkiewicz L, Sarkaria J, Schiff D, Buchanan S, Abounader R, An orally bioavailable c-Met kinase inhibitor potently inhibits brain tumor malignancy and growth., 2009; Anti-cancer agents in medicinal chemistry. 10(1) 28-35. PMID: 20015006 | PMCID: PMC3278215
2008
Kefas B, Godlewski J, Comeau L, Li Y, Abounader R, Hawkinson M, Lee J, Fine H, Chiocca EA, Lawler S, Purow B, microRNA-7 inhibits the epidermal growth factor receptor and the Akt pathway and is down-regulated in glioblastoma., 2008; Cancer research. 68(10) 3566-72. PMID: 18483236
Li Y, Guessous F, Kwon S, Kumar M, Ibidapo O, Fuller L, Johnson E, Lal B, Hussaini I, Bao Y, Laterra J, Schiff D, Abounader R, PTEN has tumor-promoting properties in the setting of gain-of-function p53 mutations., 2008; Cancer research. 68(6) 1723-31. PMID: 18339852 | PMCID: PMC3813002
Reznik TE, Sang Y, Ma Y, Abounader R, Rosen EM, Xia S, Laterra J, Transcription-dependent epidermal growth factor receptor activation by hepatocyte growth factor., 2008; Molecular cancer research : MCR. 6(1) 139-50. PMID: 18234969 | PMCID: PMC2839502
Guessous F, Li Y, Abounader R, Signaling pathways in medulloblastoma., 2008; Journal of cellular physiology. 217(3) 577-83. PMID: 18651559
Select publications from 2007 and earlier
Li Y, Guessous F, Johnson EB, Eberhart CG, Li XN, Shu Q, Fan S, Lal B, Laterra J, Schiff D, Abounader R, Functional and molecular interactions between the HGF/c-Met pathway and c-Myc in large-cell medulloblastoma., 2007; Laboratory investigation; a journal of technical methods and pathology. 88(2) 98-111. PMID: 18059365
Xu J, Gao M, Fan S, Meng Q, Goldberg ID, Abounader R, Ressom H, Laterra JJ, Rosen EM, Effect of Akt inhibition on scatter factor-regulated gene expression in DU-145 human prostate cancer cells., 2006; Oncogene. 26(20) 2925-38. PMID: 17099727
Abounader R, Laterra J, Scatter factor/hepatocyte growth factor in brain tumor growth and angiogenesis., 2005; Neuro-oncology. 7(4) 436-51. PMID: 16212809 | PMCID: PMC1871724
Li Y, Lal B, Kwon S, Fan X, Saldanha U, Reznik TE, Kuchner EB, Eberhart C, Laterra J, Abounader R, The scatter factor/hepatocyte growth factor: c-met pathway in human embryonal central nervous system tumor malignancy., 2005; Cancer research. 65(20) 9355-62. PMID: 16230398
Lal B, Xia S, Abounader R, Laterra J, Targeting the c-Met pathway potentiates glioblastoma responses to gamma-radiation., 2005; Clinical cancer research : an official journal of the American Association for Cancer Research. 11(12) 4479-86. PMID: 15958633
Beckner ME, Gobbel GT, Abounader R, Burovic F, Agostino NR, Laterra J, Pollack IF, Glycolytic glioma cells with active glycogen synthase are sensitive to PTEN and inhibitors of PI3K and gluconeogenesis., 2005; Laboratory investigation; a journal of technical methods and pathology. 85(12) 1457-70. PMID: 16170333
Abounader R, Montgomery R, Dietz H, Laterra J, Design and expression of chimeric U1/ribozyme transgenes., 2004; Methods in molecular biology (Clifton, N.J.). 252() 209-19. PMID: 15017051
Abounader R, Reznik T, Colantuoni C, Martinez-Murillo F, Rosen EM, Laterra J, Regulation of c-Met-dependent gene expression by PTEN., 2004; Oncogene. 23(57) 9173-82. PMID: 15516982
Su W, Gutmann DH, Perry A, Abounader R, Laterra J, Sherman LS, CD44-independent hepatocyte growth factor/c-Met autocrine loop promotes malignant peripheral nerve sheath tumor cell invasion in vitro., 2004; Glia. 45(3) 297-306. PMID: 14730703
Liang H, O'Reilly S, Liu Y, Abounader R, Laterra J, Maher VM, McCormick JJ, Sp1 regulates expression of MET, and ribozyme-induced down-regulation of MET in fibrosarcoma-derived human cells reduces or eliminates their tumorigenicity., 2004; International journal of oncology. 24(5) 1057-67. PMID: 15067326
Herynk MH, Stoeltzing O, Reinmuth N, Parikh NU, Abounader R, Laterra J, Radinsky R, Ellis LM, Gallick GE, Down-regulation of c-Met inhibits growth in the liver of human colorectal carcinoma cells., 2003; Cancer research. 63(11) 2990-6. PMID: 12782608
Jiang WG, Grimshaw D, Martin TA, Davies G, Parr C, Watkins G, Lane J, Abounader R, Laterra J, Mansel RE, Reduction of stromal fibroblast-induced mammary tumor growth, by retroviral ribozyme transgenes to hepatocyte growth factor/scatter factor and its receptor, c-MET., 2003; Clinical cancer research : an official journal of the American Association for Cancer Research. 9(11) 4274-81. PMID: 14519655
Moreno MJ, Abounader R, Hébert E, Doods H, Hamel E, Efficacy of the non-peptide CGRP receptor antagonist BIBN4096BS in blocking CGRP-induced dilations in human and bovine cerebral arteries: potential implications in acute migraine treatment., 2002; Neuropharmacology. 42(4) 568-76. PMID: 11955527
Bannon DI, Abounader R, Lees PS, Bressler JP, Effect of DMT1 knockdown on iron, cadmium, and lead uptake in Caco-2 cells., 2002; American journal of physiology. Cell physiology. 284(1) C44-50. PMID: 12388109
Abounader R, Ranganathan S, Kim BY, Nichols C, Laterra J, Signaling pathways in the induction of c-met receptor expression by its ligand scatter factor/hepatocyte growth factor in human glioblastoma., 2001; Journal of neurochemistry. 76(5) 1497-508. PMID: 11238734
Jiang WG, Grimshaw D, Lane J, Martin TA, Abounader R, Laterra J, Mansel RE, Abounder R, A hammerhead ribozyme suppresses expression of hepatocyte growth factor/scatter factor receptor c-MET and reduces migration and invasiveness of breast cancer cells., 2001; Clinical cancer research : an official journal of the American Association for Cancer Research. 7(8) 2555-62. PMID: 11489839
Abounader R, Lal B, Luddy C, Koe G, Davidson B, Rosen EM, Laterra J, In vivo targeting of SF/HGF and c-met expression via U1snRNA/ribozymes inhibits glioma growth and angiogenesis and promotes apoptosis., 2001; FASEB journal : official publication of the Federation of American Societies for Experimental Biology. 16(1) 108-10. PMID: 11729097
Dumont Y, Cadieux A, Doods H, Pheng LH, Abounader R, Hamel E, Jacques D, Regoli D, Quirion R, BIIE0246, a potent and highly selective non-peptide neuropeptide Y Y(2) receptor antagonist., 2000; British journal of pharmacology. 129(6) 1075-88. PMID: 10725255 | PMCID: PMC1571943
Guerin C, Luddy C, Abounader R, Lal B, Laterra J, Glioma inhibition by HGF/NK2, an antagonist of scatter factor/hepatocyte growth factor., 2000; Biochemical and biophysical research communications. 273(1) 287-93. PMID: 10873600
Bowers DC, Fan S, Walter KA, Abounader R, Williams JA, Rosen EM, Laterra J, Scatter factor/hepatocyte growth factor protects against cytotoxic death in human glioblastoma via phosphatidylinositol 3-kinase- and AKT-dependent pathways., 2000; Cancer research. 60(15) 4277-83. PMID: 10945642
Abounader R, Elhusseiny A, Cohen Z, Olivier A, Stanimirovic D, Quirion R, Hamel E, Expression of neuropeptide Y receptors mRNA and protein in human brain vessels and cerebromicrovascular cells in culture., 1999; Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism. 19(2) 155-63. PMID: 10027771
Book AA, Ranganathan S, Abounader R, Rosen E, Laterra J, Scatter factor/hepatocyte growth factor gene transfer increases rat blood-glioma barrier permeability., 1999; Brain research. 833(2) 173-80. PMID: 10375692
Abounader R, Ranganathan S, Lal B, Fielding K, Book A, Dietz H, Burger P, Laterra J, Reversion of human glioblastoma malignancy by U1 small nuclear RNA/ribozyme targeting of scatter factor/hepatocyte growth factor and c-met expression., 1999; Journal of the National Cancer Institute. 91(18) 1548-56. PMID: 10491431
Abounader R, Hamel E, Associations between neuropeptide Y nerve terminals and intraparenchymal microvessels in rat and human cerebral cortex., 1997; The Journal of comparative neurology. 388(3) 444-53. PMID: 9368852
Vogel J, Abounader R, Schröck H, Zeller K, Duelli R, Kuschinsky W, Parallel changes of blood flow and heterogeneity of capillary plasma perfusion in rat brains during hypocapnia., 1996; The American journal of physiology. 270(4) H1441-5. PMID: 8967387
Abounader R, Vogel J, Kuschinsky W, Patterns of capillary plasma perfusion in brains in conscious rats during normocapnia and hypercapnia., 1995; Circulation research. 76(1) 120-6. PMID: 8001269
Abounader R, Villemure JG, Hamel E, Characterization of neuropeptide Y (NPY) receptors in human cerebral arteries with selective agonists and the new Y1 antagonist BIBP 3226., 1995; British journal of pharmacology. 116(4) 2245-50. PMID: 8564255 | PMCID: PMC1908978